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Superoxide anion radical (O 2 ) is the primary cell-generated ROS which triggers a cascade of reactions and, therefore, the formation of secondary ROS, either directly or via enzymatic and metal-catalyzed processes, counting on the cell compartment

It aids in the breakdown of oxidized fats and is necessary for carbohydrate metabolism

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Both twins had several genetic variants associated with a higher risk of systemic inflammation

The Nox1/Nox4 inhibitor attenuates acute lung injury induced by ischemia-reperfusion in mice