doi: 10.1056/NEJMoa1504720 6 WannerCInzucchiSELachinJMFitchettDvon EynattenMMattheusMet al
It is a hormone produced by our body with numerous metabolic effects like stimulating the secretion of insulin , delaying gastric emptying , suppressing glucagon release , and signaling to the brain feelings of fullness
For example, you might feel ravenous by 11 a.m
According to DiMarchi, who worked at Eli Lilly at the time, this was much stronger validation than the acutely decreased appetite witnessed in healthy rats when given the injections of the peptide (RSC
As noted by experts at the University of Connecticut, GLP-1 peptide molecules are too large to effectively penetrate the skin barrier, making transdermal delivery of actual GLP-1 medications currently impossible with existing technology
Theres no reason not to use it