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In recent years, there has been an increase in the morbidity, disability rate,and mortality due to obesity, making it great threat to peoples health and lives, and increasing public health care expenses

This mechanism, whilst beneficial for glucose control and weight management, can lead to feelings of fullness, nausea, and potentially bloating in some individuals

The goal is finding your therapeutic dose: the lowest amount that produces meaningful weight loss without unwanted effects

For people with T2D, survodutide 1.8 mg twice weekly resulted in 9% WL vs

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The SLEEVEPASS trial demonstrated that patients who were randomly assigned to either a laparoscopy sleeve gastrectomy or a laparoscopic Roux-en-Y gastric bypass maintained a 43.5% and 50.7% excess weight loss a decade after the procedure