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Clinical studies have demonstrated that fibrotic membranes in PDR exhibit uncontrolled growth, contributing to retinal detachment from RPE cells [5]

APOM, by binding sphingosine-1-phosphate (S1P), not only triggers anti-inflammatory signaling via S1P receptors but also suppresses inflammation by inhibiting NF-B nuclear translocation through the PI3K/AKT pathway [55, 56]

DSIP is investigated as a peptide signal that may fine-tune endogenous regulatory circuits

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We agree with the applicant that the VersaVue TM Single-Use Flexible Cystoscope is not equipment, an instrument, apparatus, implement, or item of this type for which depreciation and financing expenses are recovered as depreciable assets, or a material or supply furnished incident to a service

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