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Keratinocyte differentiation markers including keratin 1, keratin 10, and involucrin demonstrate appropriate expression patterns, indicating that GHK-Cu promotes not merely rapid re-epithelialization but proper structural and functional restoration of the epidermal barrier

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Particularly, these models were characterized by increased fasting and post prandial LPS concentration, probably related to gut permeability alteration, which determined the increase of pro-inflammatory cytokines, like interleukin (IL-1) after the infusion [57]

The 1mg dose group lost an average of 2.8kg versus 0.8kg for placebo roughly 2kg of additional fat loss over 3 months