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Pirro V, Roth KD, Lin Y, Willency JA, Milligan PL, Wilson JM, Ruotolo G, Haupt A, Newgard CB, Duffin KL

While the exact mechanism isn't fully understood, headaches likely result from dehydration due to gastrointestinal side effects, blood glucose fluctuations, or metabolic changes during treatment initiation

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Importantly, the fusion proteins that remained bound to the immobilized receptor at the end of the dissociation phase, rapidly dissociated upon injection of a pH 7.4 buffer during the regeneration phase (Supplementary Fig

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