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Peptidergic sensory neurons in the control of vascular functions: Mechanisms and significance in the cutaneous and splanchnic vascular beds

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Accessed 11/29/2012 at: Freemantle N, Lafuente-Lafuente C, Mitchell S, Eckert L, Reynolds M

This process accelerates blood circulation back to the heart, potentially reducing the risk of heart attacks

78 However, the demonstration of endothelial dysfunction in the presence of increased expression of eNOS indicates that the capacity of the enzyme to produce NO may be limited, and the concept that eNOS itself can be a superoxide source and thereby contributes to endothelial dysfunction provides a further explanation to this observation

Es esencial distinguir claramente estos dos niveles de evidencia