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Abnormal sperm morphology can hinder the sperms ability to penetrate and fertilize an egg

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Methods: We identified and studied metabolites and soluble biomarkers in plasma from LC individuals mainly exhibiting ME/CFS compared to age-sex-matched recovered individuals (R) without LC, acute COVID-19 patients (A), and to SARS-CoV-2 unexposed healthy individuals (HC)

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This distinction helps you understand which data points are measured versus estimated