It can be hypothesized that under conditions of stress, caused by the presence of selenium to protect cells, a high concentration of glutathione participates in the S-thiolation process, i.e., the attachment of the -SH group of proteins to the GSH molecule [18]
This delivery system serves two purposes: Protection: It shields the glutathione from being destroyed by stomach acid
Factors such as trauma, nutritional deficiencies, irritable bowel disorders, leaky gut, microbiome dysbiosis, and immune dysregulation can all contribute to the generation of ROS, leading to tissue damage and ulcer formation
The greater the exposure to toxins, the faster the body uses up its supply glutathione
10.1177/1535370218772802 91 SioudM.WestbyP.OlsenJ
Because it works by influencing the new melanin being produced, you have to wait for your skins natural turnover cycle to see the results