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Although it shares morphologic features with cutaneous melanomas, it is biologically and genetically a distinct tumor

I would love to see that work replicated in humans and first begin with, Hey, are we even able to measure these well in humans and are we able to perturb them predictably without too much biologic noise

In the world of weight management, it is frequently used off-label because it helps reduce appetite and cravings

Further research is needed to determine the long-term sustainability of weight loss and safety of GLP-1 RAs