Controls received vehicle only, BSO-only group received 125 mg/kg twice daily on days 1, 2 and 3 via intraperitoneal injection, L-PAM-only group received 10 mg/kg dose on days 2 and 3 given intravenously into the lateral tail vein, and the L-PAM+BSO group received both drugs as per above
Due to differences in their distribution in tissues or cells and differences in known substrates, it is not known whether GPX family members can complement each other
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J Clin Investig 90:524532 Kilberg MS (1982) Amino acid transport in isolated rat hepatocytes