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High quality human clinical trials testing the combination are limited

Answer : Possibly, but side effects tend to be mild and tend to resolve without intervention once the body gets used to the supplement

2019;6:23 Mieszawska AJ, Mulder WJ, Fayad ZA, Cormode DP

It contains no water, glycerin, alcohol, preservatives, or other chemical fillers

In multiple in vitro and animal models, arginine is metabolized by iNOS to generate nitric oxide (NO), thereby enhancing pro-inflammatory responses, whereas its metabolism by Arg1 produces ornithine and polyamines that support tissue repair (3033)

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