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Symptoms of a B12 deficiency include weakness, fatigue, numbness or tingling in the hands and feet, difficulty walking, memory loss, and depression

Research Protocols & Dosing Insights Dosing parameters reported in the preclinical literature vary by species, injury model, administration route, and research objective

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Injections are more effective for those with absorption issues or severe deficiency, but oral supplements work well for most people with mild deficiency and normal absorption

If switching the route of administration and dosage don't help, you may also have like a substrate issue