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Enzymatic assays revealed that compounds 4i and 4e exhibited the best activities against tyrosinase enzyme with IC 50 values of 1.58 and 1.95 M respectively, surpassing that of the positive control kojic acid (IC 50 = 9.3 M)
additional studies to evaluate the differences in adherence to combination therapy with GLP-1RA and SGLT2i compared with SGLT2i monotherapy and how these differences impact outcomes are needed
Smitka K, Papezova H, Vondra K, Hill M, Hainer V, Nedvidkova J (2013) The Role of Mixed Orexigenic and Anorexigenic Signals and Autoantibodies Reacting with Appetite-Regulating Neuropeptides and Peptides of the Adipose Tissue-Gut-Brain Axis: Relevance to Food Intake and Nutritional Status in Patients with Anorexia Nervosa and Bulimia Nervosa
[DOI] [PubMed] [Google Scholar] 91.Webb C., Twedt D
