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Is metformin good for weight loss with PCOS
Retatrutide at the 12 mg dose with 24.2% over 48 weeks (TRIUMPH-1, NEJM 2023), followed by tirzepatide at 15 mg with 20.9% over 72 weeks (SURMOUNT-1), then semaglutide at 2.4 mg with 14.9% over 68 weeks (STEP-1)
Home monitoring provides more accurate assessment than occasional office readings
Key Takeaways Mazdutide is a dual agonist targeting GLP-1 and glucagon receptors, effective for weight management and type 2 diabetes treatment
Not only does this treatment failure burden the healthcare system with excess costs, it can also be devastating for patients who end up right back where they started
Evening administration aligns with the pineal gland's natural circadian activity
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