The reward circuit and related structures may participate in the interactions between the GLP-1 pathway and psychoactive substances, as GLP-1Rs are expressed in key brain regions like the ventral tegmental area (VTA) and the nucleus accumbens (NAc) that control reward behaviors [54]
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LSM710 and LSM880, ZEISS, Germany) was used to capture high-resolution fluorescence images, while fluorescence microscopy images were obtained using an optical microscope (SZ51, BX5, CX21, Olympus, Japan)
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