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Meta-analyses of clinical trials show a statistical association between semaglutide use and increased DVT risk (relative risk 3.66), but real-world studies involving over a million patients show the opposite trend

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Multiple research-community sources flag this combination as having been associated with hospitalizations

Arthritis Rheum 2006;54:2295-2299

Chondrocyte senescence (Zhu et al., 2021): Selectively removed senescent cells from human chondrocyte cultures, with implications for cartilage repair

Ensure you are adequately hydrated, and if you are diabetic, check your blood glucose levels