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5FU adaptation alters mitochondrial activity Given the changes in mitochondrial abundance, without evident mitochondrial dysfunction (no cristae clearing, no change in apoptotic priming, no release of cytochrome c or mtDNA), we reasoned that the increase might be associated with increased functionality

Am J Med Genet B Neuropsychiatr Genet 147B:11451151 Deth R, Muratore C, Benzecry J, Power-Charnitsky VA, Waly M (2008) How environmental and genetic factors combine to cause autism: a redox/methylation hypothesis