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For pathohistological evaluation transversal sections of crushed muscle, longitudinal section of transected muscle and longitudinal section of transected tendon were used
Of these 47, 89% saw multi-system improvement within days of taking the GLP1-RA and in some cases improvements were observed within a 24 hour period, These improvements were related to symptoms that were inflammatory in nature
Furthermore, ALC pretreatment reduced GFAP expression in the striatum, which may be connected to its anti-inflammatory action (Afshin-Majd et al
Novo also reported in early 2026 that CagriSema showed superior HbA1c reduction and weight loss vs semaglutide in a Phase 3 diabetes program (REIMAGINE 2)
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