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Igarashi T, Nanba E, Sagami F, Tsukidate K, Fukuda T, Horie T, et al

It can reduce inflammation and oxidative stress, both key contributors to heart disease

Despite the guideline-recommended use of both SGLT2i and GLP-1RA therapy, there is a paucity of real-world evidence on the long-term effects of combining SGLT2is with newer generation GLP-1RAs (including once-weekly GLP-1RAs, once-daily oral semaglutide, and dual GLP-1/glucose-dependent insulinotropic polypeptide [GIP] agonists) on metabolic outcomes and other cardiorenal outcomes [22]

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Sadr SS et al

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