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Real-World Analysis (November 2025): A landmark study published in Science Daily (November 12, 2025) found that both semaglutide (Ozempic) and tirzepatide (Mounjaro) offer similar levels of heart protection , with only small differences in results

Leptin may act directly on the NTS, AP, or dorsal motor nucleus of the vague nerve and even influence the response of CCK [20], or finally induces satiety through the activation of POMC neurons in the VMH [12]

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