The GLP-1 and dual GIP/GLP-1 RAs available in the UK include dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide
This move comes as June saw 3,763 active lawsuits in the GLP-1 MDL
Additionally, studies in patients with T2DM are now needed to explore potential clinical benefits [197]
Results confirmed positive impact of GLP-1 receptor agonists on MACE outcomes in patients with T2D but also revealed promising trends regarding heart failure outcomes in terms of reduced rate of heart failure-related events ( In conclusion, GLP-1 receptor agonists show potential in heart failure management through their multiple mechanisms of action, including direct cardioprotective effects, vasodilation, natriuresis, and glucose and weight control
The NTS is the main source of endogenous GLP-1 within the brain (Holt et al., 2019)
Patients should never hesitate to contact their healthcare provider with concerns about their treatment