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Activated fibroblast-like synoviocytes (FLS) of the synovial membrane have been identified as key drivers, secreting humoral mediators that maintain inflammatory processes, proteases that cause cartilage and bone destruction, and factors that drive fibrotic processes

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GLP1 hair loss often improves once the trigger stabilizes, but visible regrowth still takes months

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References El Ansari W, Elhag W