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For GI healing, 2 weeks may be sufficient based on published animal data showing rapid mucosal repair

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Severe gastrointestinal conditions: Those with delayed gastric emptying, gastroparesis, or chronic GI dysmotility may experience exacerbated symptoms due to the drugs action on gastric motility

It is thought to influence the sleep-wake cycle by affecting neurotransmitter activity, including that of gamma-aminobutyric acid (GABA) and serotonin

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Step 2: Remove your retatrutide vial from the refrigerator Allow the vial to sit at room temperature for 15 to 30 minutes before injection