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While both IGF-1 LR3 and IGF-1 DES activate the same receptor (IGF1R), their half-lives, delivery methods, and mechanisms of action lead to different safety profiles

[DOI] [PubMed] [Google Scholar] 73.Ferdouse A., Agrawal R.R., Gao M.A., Jiang H., Blaner W.S., Clugston R.D

Pharmacological inhibition and IGF-1R-targeted knockdown reverse the effects of t-Darpp on metabolic remodeling and drug resistance in tumor cells (66)

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