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Common side effects include nausea, diarrhoea, and constipation, typically diminishing with gradual dose escalation and ongoing use

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However, CMS announced the Medicare GLP-1 Bridge demonstration in December 2025, which will allow Medicare beneficiaries to access GLP-1 obesity medications starting July 2026 , with a longer-term BALANCE Model launching in Medicare Part D by January 2027 ( [18] )

In A-treated astrocytes, GLP-1 prevented mitochondrial fragmentation, and improved the neuronal supportive ability via cAMP/PKA pathway (188)

Plant-based proteins such as tofu, tempeh, lentils, and chickpeas offer fiber alongside amino acids, creating a double benefit: sustained fullness and improved gut health

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