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Further studies are required to elucidate how this mutation influences thyroid function without immediately altering thyroid hormone levels, as also noted by Pfffle et al

Additionally, the magnitude of clinical effects differs substantially

The use of GLP-1 agonists has been associated with significant total body weight loss (fat and lean mass), with lean mass representing approximately 25% of total body weight loss [9]

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The drug manufacturer, Eli Lilly, has conducted these studies to assess the drugs impact on weight management