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M-CuP has antioxidant activity by increasing antioxidant enzymes and superoxide dismutase (SOD) activity, mainly neutralizing ROS by scavenging harmful oxygen-derived free radicals 66

For example, a meta-analysis of 31 randomized, controlled trials reports that the most common side effects observed in the hGH studies and their respective incidences were [16]: Soft tissue edema: 50% Insulin resistance: 22% Arthralgias: 21% Carpal tunnel syndrome: 19% These side effects are transient and usually subside as the patient gets used to the therapy

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Blood 104:274b, 2004

Severe niacin deficiency, known as pellagra, has been historically associated with poverty and consumption of a diet predominantly based on corn, which is low in bioavailable niacin (25, 26)

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