Patients seek treatment for medically-confirmed B12 deficiency causing fatigue, neurological symptoms, or anemia
Redness, itching, or mild irritation at the application site can occur, particularly during initial use or with higher concentrations
The muscle acts as a reservoir, releasing B12 gradually into the bloodstream over hours to days
Its likewise crucial to note that, as with any supplement, especially one that is relatively new and not extensively studied, caution must be exercised regarding its use
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Most preclinical trials used weight-adjusted dosing (mg/kg) that doesn't translate directly to fixed human protocols