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Brenipatide brings metabolic and reward-circuit biology together: leveraging mechanisms traditionally seen in obesity/diabetes into addiction

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Also known as the Barbie drug, melanotan II is an unregulated, synthetic hormone believed to stimulate pigment cells and encourage melanin production

In all, the insurer reported a $301 million operating loss on $9.8 billion in revenue

While some metabolic adaptation still occurs, the direct appetite suppression provided by the medication means that the ghrelin increase is less impactful

10.1021/acs.orglett.6b03608 Org