Dose titration and administration : According to the Ozempic SmPC, treatment is initiated at 0.25 mg once weekly for four weeks, then increased to 0.5 mg weekly
Burde R, Schainker B, Kayes J
Neuroprotective effects of intrastriatal injection of rapamycin in a mouse model of excitotoxicity induced by quinolinic acid
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Initially its 0.6mg once daily, increasing each week by 0.6mg, if tolerated and under the supervision of your prescriber, up to a maximum of 3mg daily
In addition, it also downregulates Macrophage inflammatory protein-1 alpha (MIP-1) and Macrophage inflammatory protein-1 beta (MIP-1)