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Over time, frequent use can also push the body toward insulin resistance, creating long-term metabolic issues

Study in 472 normally growing children

It appears to modulate neurotransmitter systems, including dopamine and serotonin, and has shown efficacy in counteracting damage induced by various neurotoxins, suggesting potential applications in neurological conditions like Parkinson's disease and schizophrenia-like models

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Estradiol helps determine food intake and metabolic rate, both of which change during the menstrual cycle in response to hormone fluctuations

Interestingly, Gabery et al