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Proportion of basal and stimulated PBMC, as well as MFI of these cells, varied significantly over time, with pronounced changes around parturition and without any effect of CAR supplementation

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Data collection reflected routine clinical practice rather than mandatory assessments at prespecified time points, which may impact the amount of available data and its interpretation

Using a human Burkitt lymphoma model P493 cell line carrying an inducible MYC vector, the group showed the coexistence of oxidative and aerobic glycolysis

2 Establishes GLP-1RAs are engineered to overcome the rapid degradation of native GLP-1 through DPP-4resistant modifications and exposure-extending strategies such as fatty-acid acylation, enabling sustained receptor occupancy