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A pharmacological probe identifies cystathionine beta-synthase as a new negative regulator for ferroptosis

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Lifshitz GV, Zhdanov DD, Lokhonina AV, Eliseeva DD, Lyssuck EY, Zavalishin IA, et al

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[Confidence: Medium] Organ-Specific Targeting: By isolating the hippocampus, the researchers confirmed that GHK-Cu can cross the blood-brain barrier (or bypass it via olfactory tracts) to modulate neuroinflammation and synaptic plasticity, which are critical bottlenecks in age-related cognitive decline