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As well, recent methodologies in PD research have shifted from focusing solely on dopamine-replenishing symptomatic therapies to personalized therapeutics aimed at restoring the molecular, anatomical, and functional integrity of specific brain circuits affected by the disease

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J Endocrinol Invest (2017) 40:839

Original Discovery Published McCoy et al

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At this time, we believe the timing parameters for invitation issuance and the proposed 65-day response window are appropriate to support valid, comparable measurement across facilities while balancing operational feasibility