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Last but not least, we acknowledge researchers who generated the experimental aqueous solubility data and released them for public use

10.1101/sqb.2011.76.011023 Cold

AMA Style Roy, S

ZN: Data curation, Investigation, Writing original draft, Writing review and editing

Yet, as with NRF2, tumor contexts complicate interpretation: HO-1 is overexpressed in some cancers, including HCC, where it actively supports tumor progression by enhancing survival via mechanisms such as increasing cancer cell proliferation, conferring resistance to chemo- and radiotherapy, and promoting angiogenesis, as indicated by its strong correlation with VEGF expression and microvascular invasion

These include epigastric pain syndrome, functional dysphagia, heartburn, reflux hypersensitivity, belching disorder, bloating/distention, centrally mediated abdominal pain, fecal incontinence, and others