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Theres also likely a hormonal factor: Youre losing facial fat, which acts as an endocrine organ, producing hormones like estrogen, and estrogen is important to the integrity of your skin, says Dr

[DOI] [PMC free article] [PubMed] [Google Scholar] Vickneson K, George J

van Huisstede A, Rudolphus A, Castro Cabezas M, et al

Its important to remember that while B12 injections can address fatigue related to deficiency, they are not a universal solution for tiredness caused by other medical or lifestyle factors