GLP-1 receptor agonists work by mimicking the action of naturally occurring GLP-1, a hormone released from the intestine after eating
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Males typically carry more visceral fat around organs, which responds more aggressively to GLP-1 receptor activation than subcutaneous fat
To ascertain the obesity-specific role of TMPRSS2 in regulating postprandial glucose homeostasis, we employed an independent preclinical model of obesity (db/db mice) and performed a pharmacological intervention with a TMPRSS2 inhibitor
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