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In a study conducted on Japanese patients with T2DM, those who received tirzepatide doses ranging from 5 to 15 mg for 52 weeks experienced a significant decrease in HbA1c levels by 2.43.02%

These changes can affect identity, self-image, and relationships, especially for individuals with a history of shame, stigma, or disordered eating

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Rates of depression were 44% lower, and anxiety disorders were 38% lower during periods of semaglutide use

For these reasons, limited treatment options exist for this patient population

2.4 Study covariates We carefully selected a comprehensive set of covariates for analysis, ensuring that these variables were obtained either on or within one year prior to the index date