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J Neuro-Oncol 19:239253 Fiala M, Murphy T, MacDougall J, Yang W, Luque A, Iruela-Arispe L, Cashman J, Buga G, Byrns RE, Barbaro G, Arthos J (2004) HAART drugs induce mitochondrial damage and intercellular gaps and gp120 causes apoptosis

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In addition, considering the important concept, cytoprotection (initially based on the essential consistent ulcerogenic role of NSAIDs agents (25)) can now provide the consistently demonstrated NSAIDs-sphincter failure as an additional clue to further accommodate all of the NSAIDs effects