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178,179,180 In 2004, the FDA approved the first aptamer drug, pegaptanib (Macugen), to treat choroidal neovascularization caused by neovascular age-related macular degeneration (AMD)

And it is rational to ramp up this metabolic rate

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and Played a pivotal role in advocating for, implementing or advancing global health policies and/or programs that improve the health of people and the planet