Ongoing research explores various therapeutic approaches, including natural compounds, endogenous substances, and repurposed drugs, to mitigate DOX-induced cardiotoxicity
In the SURMOUNT-2 study, which involved 938 adults with obesity or overweight and T2D, tirzepatide showed significant weight loss effects of 13.4% and 15.7% for the 10 and 15 mg doses, respectively, with over 80% of participants experiencing at least a 5% weight loss [92]
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According to the diagnostic interval between type 2 diabetes mellitus (T2DM) and PDA, DM was divided as the long-standing diabetes mellitus (time interval longer than 3 years) and the new-onset diabetes mellitus (time interval shorter than 3 years) (Jeon et al., 2018)
They are not intended to represent clinical evidence in humans, and 5-Amino-1MQ has not been approved by the FDA, EMA, or any other regulatory authority for any indication
10.1007/s10616-025-00793-9 82 LiL.LiP.HeY.XuZ.FanY.JiaX.et al (2025)
