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It acts as an intracellular antioxidant and promotes powerful anti-aging effects

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P-288 changes in gene and protein expression in human endometrial cancer cell lines after low dose metformin treatment over time

This pathway is tightly regulated by enzymes such as ornithine aminotransferase (OAT) and pyrroline-5-carboxylate reductase (PYCR), which control proline production and, consequently, the rate of collagen deposition [13,14,15,16]

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