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Brief exposure to room temperature is usually fine, but extended warm-storage shortens shelf life

Additionally, adequate maternal B12 is crucial for both mother and child, supporting maternal health and reducing the risk of neurological and metabolic complications

Neurological benefits including improved outcomes in demyelinating disease models point to CNS effects

Peer review Peer review information Nature Reviews Drug Discovery thanks Kevin Gardner and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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By considering the pharmacokinetic factors that determine the dose-concentration relationship, it is possible to individualize the dose regimen to achieve the target concentration