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Enzymatic properties, evidence for in vivo expression, and intracellular localization of shewasin D, the pepsin homolog from Shewanelladenitrificans

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When cells are stimulated, the dynamic balance of this microenvironment may be disrupted, leading to the development and progression of pancreatic diseases, such as diabetes and pancreatitis (Figure 2)

Additionally, GGCT knockdown concomitantly reduced 5- oxoproline (5-OP) levels in MHCC97H cells, consistent with 5-OP being the direct enzymatic product of GGCT activity, and exogenous 5-OP rescued proliferation under Gln-deprived conditions (Fig

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