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NAC, in particular, has been shown to increase glutathione levels in the liver and other tissues (1)

Biol Chem 383:489502 Qi W, Cowan JA (2011) Mechanism of glutaredoxin-ISU [2Fe2S] cluster exchange

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The endothelial cell dysfunction induced by oxidized LDL is one of the first steps in the development of arteriosclerosis, so the adaptive vascular responses and /or oxidative stress protectors are important in the prevention of arteriogenesis (55)