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In 1871, the first accurate description of the disease in continental Europe was made by Michael Anton Biermer, a German physician who noted the insidious course of the condition

The results have been remarkable

Nociplastic pain criteria or recognition of central sensitization

12 In CD patients with IgA deficiency (which is estimated to occur in 2% of CD patients), the detection of deaminated gliadin peptide IgG, and tTG IgG antibodies is recommended

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