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This condition is typically painless but can cause sudden, irreversible vision loss
Surprisingly, a daily activation of GPR119 with OEA or other synthetic agonists, increases -cell responsiveness in islets transplanted into STZ-induced diabetic mice (328)

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Discontinuation rates improved from TRIUMPH-4 (18.2%) to TRIUMPH-1 (11.3%) to TRANSCEND-T2D-1 (5.1%)
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