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Patients with a history of gallstones, previous cholecystitis, or known cholelithiasis on imaging should discuss these conditions with their healthcare provider before starting therapy

Possible temporary effects include: Mild redness or swelling Dryness during treatment course Serious complications remain uncommon

Both have FDA-approved uses for chronic weight management in adults with obesity or who are overweight with a weight-related condition, in addition to type 2 diabetes uses

These benefits arise because reduced immunologically mediated tissue damage allows endocrine cues to be interpreted and responded to more consistently