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van Dijk et al., 2013b), decreased -fucosidase (van Dijk et al., 2013b), -glucocerebrosidase decreased (Balducci et al., 2014a) or normal (van Dijk et al., 2013b), -galactosidase increased (van Dijk et al., 2013b) or normal (Balducci et al., 2014a), and cathepsin D normal (van Dijk et al., 2013b) in PD patients compared with controls

This means results may plateau if caloric intake drifts upward, as AOD-9604 enhances fat oxidation but does not override positive energy balance

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Furthermore, 19.6% of participants in the placebo group increased their antihypertensive treatment (compared with 8.4% with CagriSema), which may have impacted the ETD in BP between these groups

Patients should seek medical attention for persistent right upper quadrant or epigastric pain, fever, or jaundice

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